منابع مشابه
To DNA, all information is equal
Information storage capabilities are key in most aspects of society and the requirement for storage capacity is rapidly expanding. In principle, DNA could be a high-density medium for information storage. Church and coworkers recently demonstrated how binary data can be encoded, stored in, and retrieved from a library of oligonucleotides, increasing by several orders of magnitude the amount and...
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Cardiac hypertrophy is the natural response of myocardium to various stressors, including neurohormonal stimuli, hemodynamic overload, and injury. In the face of continued stress, pathological hypertrophy progresses to a loss of cardiomyocytes, the development of fibrosis, and, ultimately, heart failure. Emerging evidence has shown that glycogen synthase kinase-3 (GSK-3 ) is an important negati...
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Only recently have approaches to quantitative information flow started to challenge the presumption that all leaks involving a given number of bits are equally harmful. This paper proposes a framework to capture the semantics of information, making quantification of leakage independent of the syntactic representation of secrets. Secrets are defined in terms of fields, which are combined to form...
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1. National Institute for Health and Clinical Excellence. Core interventions in the treatment and management of schizophrenia in primary and secondary care (update). Clinical Guidelines CG82, issued March 2009. http://www.nice.org.uk/guidance/ index.jsp?action=byID&o=11786 (accessed 29 July 2009). 2. Kendell R. The distinction between personality disorder and mental illness. Br J Psychiatry 200...
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By sequencing tens of millions of TCRa transcripts from naive mouse CD8 T cells, Genolet et al (2012) show that the TCRa repertoire is at least as diverse as the TCRb repertoire. This overturns a long held view in the field that recombination of the Tcra locus occurs in a co-ordinate sequential bidirectional manner that relies on proximity of Va and Ja gene segments. The observation that rearra...
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ژورنال
عنوان ژورنال: Artificial DNA: PNA & XNA
سال: 2012
ISSN: 1949-095X,1949-0968
DOI: 10.4161/adna.22671